Pharmaceutical spray drying with LEWA diaphragm metering pumps

Pharmaceutical, biotechnological products, food or plant extracts for personal hygiene products and also fine chemicals dry fast through maximizing of the surface of the wet products.

LEWA diaphragm metering pumps from the hygienic und sanitary series in triplex design are perfect for reliable and safe metering in the spray drying process in the GMP environment.

Solutions

Advantages of LEWA diaphragm metering pumps for pharmaceutical spray dryers:

  • Hermetically sealed, no contaminants can get in or out
  • Easy-to-clean design, easy accessibility for maintenance purposes
  • High security thanks to 4-layer sandwich diaphragm with diaphragm monitoring and signaling without product contamination
  • Clean operation – no particle abrasion in the LEWA pump
  • Hygienic design, specially developed with and for the pharmaceutical industry (GMP-compliant)
  • Coating of spray dryer nozzles with constant pressure through a rigid pump curve
  • Gentle conveyance, no high shear forces
  • Low hold-up in the pump head thanks to design with minimized dead space
  • CIP; SIP; DIP
  • FAT, SAT and global service

Options:

  • Material 1.4435 (AISI 316L) with a surface roughness of Ra < 0.5µm
  • Inert and FDA compliant construction materials
  • Ex-proof protection, ATEX conformity
  • According to ASME BPE
  • Comprehensive documentation for qualification

LEWA is a member of leading committees for the hygienic design of pumps and systems.

QHD Certificate

QHD Certificate

Areas of application

LEWA metering pumps are used, for example, for:

  • Aqueous solutions, suspensions and emulsions
  • Compositions based on organic solvents, such as ethanol, isopropanol, acetone or methylene chloride

Filler, binder, disintegrants, sliding agents can thus be dissolved or suspended and transferred with the active material in defined, dry, free flowing, uniform particles.

Background

The fundamental concept of spray drying

The production of finely dispersed powder from a wet charging fluid by vaporizing the liquid:

  • A solution /suspension is sprayed via nozzles or rotating disk atomizers into a hot air or nitrogen flow
  • The supply to the spray drying system uses suitable pumps. Drying and particle formation are done simultaneously in the spraying process during this process. Due to these higher requirements on the pharmaceutical technology, the demands which are put on the bioavailability of a drug also increase. The effectiveness of a drug also depends on the generated particle size, after all.

Important customer requirements for this are:

  1. Particle size distribution
  2. Percentage of residual moisture
  3. Bulk density and particle shape
  4. Maintaining exact and consistent quality standards
  5. Precise, continuing, safe and
  6. low-pulsation fluid supply
Pharma Spray drying

Process scheme pharmaceutical spray drying

Industries

Personal care

LEWA is your reliable partner in the production of personal care products. Our systems meet the strictest quality and hygiene requirements. Ask us for more information!

Pharma, Life Science & Biotech

LEWA supplies pumps and systems for the pharmaceutical, life sciences, and biotech industries that comply with all hygienic requirements. We're happy to help you!

Food & Beverage

Use LEWA pumps and system solutions for your homogenization processes in the food and beverage industry. Ask our experts for more information!

Products

LEWA ecoflow® sanitary/hygienic diaphragm metering pump

ecoflow sanitary hygienic pump The ecoflow® diaphragm dosing pump in sanitary / hygienic version is the ideal pump for food and pharmaceutical production.

LEWA ecodos® sanitary/hygienic diaphragm metering pump

LEWA ecodos sanitary/hygienic diaphragm metering pump The LEWA ecodos® diaphragm metering pump with its sanitary/hygienic design is the ideal pump for food and pharmaceutical products in the low-pressure range.

LEWA intellidrive® diaphragm metering pump

LEWA intellidrive diaphragm metering pump Use servomotor-controlled diaphragm metering pumps for precision metering and mixing of fluids in metering plants and systems.

LEWA ecoflow® process pumps for high-pressure applications

LEWA ecoflow process pump The LEWA ecoflow process diaphragm pump is the top performer among innovative and universal process pumps for high-pressure process technology.

LEWA triplex® process pumps for high-pressure processes

LEWA triplex process pump LEWA triplex is the most compact process pump in the world for high-pressure processes in all branches of industry. Contact us, we are happy to help!

Customer-Specific Metering, Mixing or Filling Systems from LEWA

LEWA production units LEWA develops customized production units for metering, mixing, and filling fluids. Contact us and let us advise you!

Customer-Specific Metering Systems from LEWA

LEWA customer specific metering systems LEWA provides you with custom-designed metering systems according to your specifications. Trust in our experience gained from 60 years of metering technology.

Get updates

Subscribe to our newsletter!

Get LEWA insights on products, applications and the business of metering fluids. Subscribe now for free.

Follow us

LEWA is on Linkedin LEWA is on YouTube
© 2019 LEWA GmbH
© 2019 LEWA GmbH